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Therapeutics, Evidence and Decision-Making

Therapeutics, Evidence and Decision-Making PDF Author: Michael D Rawlins
Publisher: CRC Press
ISBN: 1853159476
Category : Law
Languages : en
Pages : 246

Book Description
This book is intended to help decision-makers use, assess and appraise the evidence that underpins decisions about the use of therapeutic interventions. It will inform decision-makers about the nature of evidence, the strengths and weaknesses of the available approaches, and how these can be most effectively distilled for the purpose of reaching reliable conclusions. It aims to encourage decision-makers to base their judgements about the use of therapeutic interventions on an informed appraisal of the totality of the evidence base. Is it reliable? Is it generalisable beyond the context of the environment in which the primary research has been conducted? Do the intervention's benefits outweigh its harms? Is it cost effective as well as clinically effective? Is it, indeed, fit-for-purpose? Ultimately, good judgement is at the heart of decision-making in therapeutics. An invaluable text for all physicians, pharmacists, nurses, health commissioners and purchasers and indeed anyone having to make decisions concerning evidence-based therapeutics.

Therapeutics, Evidence and Decision-Making

Therapeutics, Evidence and Decision-Making PDF Author: Michael D Rawlins
Publisher: CRC Press
ISBN: 1853159476
Category : Law
Languages : en
Pages : 246

Book Description
This book is intended to help decision-makers use, assess and appraise the evidence that underpins decisions about the use of therapeutic interventions. It will inform decision-makers about the nature of evidence, the strengths and weaknesses of the available approaches, and how these can be most effectively distilled for the purpose of reaching reliable conclusions. It aims to encourage decision-makers to base their judgements about the use of therapeutic interventions on an informed appraisal of the totality of the evidence base. Is it reliable? Is it generalisable beyond the context of the environment in which the primary research has been conducted? Do the intervention's benefits outweigh its harms? Is it cost effective as well as clinically effective? Is it, indeed, fit-for-purpose? Ultimately, good judgement is at the heart of decision-making in therapeutics. An invaluable text for all physicians, pharmacists, nurses, health commissioners and purchasers and indeed anyone having to make decisions concerning evidence-based therapeutics.

Handbook of Institutional Pharmacy Practice

Handbook of Institutional Pharmacy Practice PDF Author: Thomas R. Brown
Publisher: ASHP
ISBN: 158528114X
Category : Medical
Languages : en
Pages : 592

Book Description
This comprehensive text provides fundamental information on a broad spectrum of essential topics in health-system pharmacy practice. From an overview of health delivery systems and hospital pharmacy through various practice settings such as home care, long term care, hospice and palliative care, ambulatory care, and managed care this text focuses on various elements important to health-system pharmacies. The Handbook of Institutional Pharmacy Practice is the first step in developing a career in pharmacy and provides opportunities for study in career enhancement. New chapters included in the fourth edition: Integrity of the Drug Supply Overview of the History of Hospital Pharmacy in the United States Interprofessional Teams/Collaborative Practice Models Development, Implementation and Monitoring Therapeutic Plans and Evidence-Based Medicine

Real-World Evidence Generation and Evaluation of Therapeutics

Real-World Evidence Generation and Evaluation of Therapeutics PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309455650
Category : Medical
Languages : en
Pages : 102

Book Description
The volume and complexity of information about individual patients is greatly increasing with use of electronic records and personal devices. Potential effects on medical product development in the context of this wealth of real-world data could be numerous and varied, ranging from the ability to determine both large-scale and patient-specific effects of treatments to the ability to assess how therapeutics affect patients' lives through measurement of lifestyle changes. In October 2016, the National Academies of Sciences, Engineering, and Medicine held a workshop to facilitate dialogue among stakeholders about the opportunities and challenges for incorporating real-world evidence into all stages in the process for the generation and evaluation of therapeutics. Participants explored unmet stakeholder needs and opportunities to generate new kinds of evidence that meet those needs. This publication summarizes the presentations and discussions from the workshop.

PHARMACOTHERAPEUTICS

PHARMACOTHERAPEUTICS PDF Author: Dr. Omveer Singh
Publisher: Blue Rose Publishers
ISBN:
Category : Education
Languages : en
Pages : 211

Book Description
This book is companion to pharmacotherapy: a pathophysiologic approach is designed to provide practitioners and students with critical information that can be easily used to guide drug therapy decision making in the clinical setting. To ensure brevity and portability, the user with essential textual information, key tables and figures, and treatment algorithms are incorporated. Corresponding to the major sections in the main text, disorders are following sections: cardiovascular system, respiratory system, endocrine system, central nervous system, gastrointestinal disorders, hematological disorders, infectious diseases, musculoskeletal disorders, dermatology, psychiatric disorders, ophthalmology, antimicrobial resistance, women’s health is well explained. Carrying over a popular feature from Pharmacotherapy, each chapter is organized in a consistent format: Definition, etiopathogenesis, clinical manifestations, Non-pharmacological and pharmacological management of the diseases associated. The treatment section may include Nonpharmacologic therapy, drug selection guidelines, dosing recommendations, adverse effects, pharmacokinetic considerations, and important drug–drug interactions are well explained.

The Routledge Companion to Philosophy of Medicine

The Routledge Companion to Philosophy of Medicine PDF Author: Miriam Solomon
Publisher: Taylor & Francis
ISBN: 131751985X
Category : Philosophy
Languages : en
Pages : 564

Book Description
The Routledge Companion to Philosophy of Medicine is a comprehensive guide to topics in the fields of epistemology and metaphysics of medicine. It examines traditional topics such as the concept of disease, causality in medicine, the epistemology of the randomized controlled trial, the biopsychosocial model, explanation, clinical judgment and phenomenology of medicine and emerging topics, such as philosophy of epidemiology, measuring harms, the concept of disability, nursing perspectives, race and gender, the metaphysics of Chinese medicine, and narrative medicine. Each of the 48 chapters is written especially for this volume and with a student audience in mind. For pedagogy and clarity, each chapter contains an extended example illustrating the ideas discussed. This text is intended for use as a reference for students in courses in philosophy of medicine and philosophy of science, and pairs well with The Routledge Companion to Bioethics for use in medical humanities and social science courses.

Big Data in Radiation Oncology

Big Data in Radiation Oncology PDF Author: Jun Deng
Publisher: CRC Press
ISBN: 1351801120
Category : Science
Languages : en
Pages : 289

Book Description
Big Data in Radiation Oncology gives readers an in-depth look into how big data is having an impact on the clinical care of cancer patients. While basic principles and key analytical and processing techniques are introduced in the early chapters, the rest of the book turns to clinical applications, in particular for cancer registries, informatics, radiomics, radiogenomics, patient safety and quality of care, patient-reported outcomes, comparative effectiveness, treatment planning, and clinical decision-making. More features of the book are: Offers the first focused treatment of the role of big data in the clinic and its impact on radiation therapy. Covers applications in cancer registry, radiomics, patient safety, quality of care, treatment planning, decision making, and other key areas. Discusses the fundamental principles and techniques for processing and analysis of big data. Address the use of big data in cancer prevention, detection, prognosis, and management. Provides practical guidance on implementation for clinicians and other stakeholders. Dr. Jun Deng is a professor at the Department of Therapeutic Radiology of Yale University School of Medicine and an ABR board certified medical physicist at Yale-New Haven Hospital. He has received numerous honors and awards such as Fellow of Institute of Physics in 2004, AAPM Medical Physics Travel Grant in 2008, ASTRO IGRT Symposium Travel Grant in 2009, AAPM-IPEM Medical Physics Travel Grant in 2011, and Fellow of AAPM in 2013. Lei Xing, Ph.D., is the Jacob Haimson Professor of Medical Physics and Director of Medical Physics Division of Radiation Oncology Department at Stanford University. His research has been focused on inverse treatment planning, tomographic image reconstruction, CT, optical and PET imaging instrumentations, image guided interventions, nanomedicine, and applications of molecular imaging in radiation oncology. Dr. Xing is on the editorial boards of a number of journals in radiation physics and medical imaging, and is recipient of numerous awards, including the American Cancer Society Research Scholar Award, The Whitaker Foundation Grant Award, and a Max Planck Institute Fellowship.

The New Navigators

The New Navigators PDF Author: Robert Baud
Publisher: IOS Press
ISBN: 9781586033477
Category : Medical
Languages : en
Pages : 936

Book Description
The extensive use of the web by patients and laymen for health information, challenges us to build information services that are easily accessible and trustworthy. The evolution towards a semantic web is addressed and papers covering all the fields of biomedical informatics are also included. [Ed.].

Cardiovascular Therapeutics E-Book

Cardiovascular Therapeutics E-Book PDF Author: Elliott M. Antman
Publisher: Elsevier Health Sciences
ISBN: 1455737372
Category : Medical
Languages : en
Pages : 833

Book Description
Manage cardiovascular problems more effectively with the most comprehensive resource available! A trusted companion to Braunwald's Heart Disease, Cardiovascular Therapeutics, 4th Edition addresses pharmacological, interventional, and surgical management approaches for each type of cardiovascular disease. This practical and clinically focused cardiology reference offers a balanced, complete approach to all of the usual and unusual areas of cardiovascular disease and specific therapies in one concise volume, equipping you to make the best choices for every patient. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Understand current approaches to treating and managing cardiovascular patients for long-term health, for complex problems, and for unusual cardiac events. Benefit from the substantial experience of Elliott M. Antman, MD, Marc S. Sabatine, MD, and a host of other respected authorities, who provide practical, evidence-based rationales for all of today's clinical therapies. Expand your knowledge beyond pharmacologic interventions with complete coverage of the most effective interventional and device therapies being used today. Easily reference Braunwald's Heart Disease, 9th Edition for further information on topics of interest. Make the best use of the latest genetic and molecular therapies as well as advanced therapies for heart failure. Cut right to the answers you need with an enhanced focus on clinically relevant information and a decreased emphasis on pathophysiology. Stay current with ACC/AHA/ESC guidelines and the best ways to implement them in clinical practice. Get an enhanced visual perspective with an all-new, full-color design throughout.

Time-limited Psychodynamic Psychotherapy with Children and Adolescents

Time-limited Psychodynamic Psychotherapy with Children and Adolescents PDF Author: Ruth Schmidt Neven
Publisher: Taylor & Francis
ISBN: 1317216857
Category : Psychology
Languages : en
Pages : 146

Book Description
At a time when there is increasing concern about the escalation of child and adolescent mental health problems, Time-limited Psychodynamic Psychotherapy with Children and Adolescents provides an innovative contextual model that engages the child or young person and their parents. The core of the model is the recognition of the dynamic capacity for growth in the child and how this, in itself, creates opportunities for effective treatment over a relatively short period of time. Based on evidence that the most enduring therapeutic outcomes involve a shift in the parents’ relational understanding of themselves, as well as a change in the child, the book uses case examples to show how this model can be applied in everyday therapeutic practice. Time-limited Psychodynamic Psychotherapy with Children and Adolescents is aimed at practitioners in the field of child, adolescent, parent and family psychotherapy. It will interest psychologists, child psychotherapists, doctors, psychiatrists, social workers and mental health workers.

Multiple Sclerosis Therapeutics

Multiple Sclerosis Therapeutics PDF Author: Jeffrey A. Cohen
Publisher: Cambridge University Press
ISBN: 1139502379
Category : Medical
Languages : en
Pages :

Book Description
This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.